Nine NFL playoff teams from last season lost in Week 2.That left the door for some playoff upstarts for 2022 to make their case for this season.Baltimore and Miami just mi sed the postseason in 2021. Now, they meet in Week 2 in what should be one of the best games of the week. Lamar Jackson could get JK Dobbins back, and Tua Tagovailoa has improved with the help of Tyreek Hill and Jaylen Waddle. That game might not have the hype of the Thursday Night Football showdown between the Chiefs and Chargers, but it will be just as entertaining from a scoring standpoint.The Vikings also made a statement in Week 1 with a 23-7 victory against Green Bay. While the Packers will look to avoid a 0-2 start against rival Chicago on Sunday Night Football; Minnesota can a sert early control of the NFC North at Philadelphia.Which teams will go 2-0? 0 Junior Seau Jersey -2? Each week, SN will pick the NFL games straight up and against the spread. Last week, we finished 7-8-1. Hey, it's Week 1, right?Here are our straight-up picks for Week 2 (lines courtesy of Caesars):POWER RANKINGS: Los Angeles Chargers at Kansas City Chiefs (-3.5)This is a rematch of last year's TNF thriller the Chiefs won 34-28 in overtime. The road team has won the last four meetings, too. Six different Kansas City players scored TDs in Week 1. The Chargers need to get a running game going behind Justin Herbert, who might be without Keenan Allen (hamstring). The home team breaks through here.Pick: Chiefs 32, Chargers 27Result: Chiefs 27, Chargers 24New York Jets at Cleveland Browns (-4.5)Joe Flacco is 17-3 against the Browns as a starter, but that was with the Ravens. The Jets were 2 of 14 on third down against Baltimore, and that means Cleveland will turn Myles Garrett loose. It's another dose of Nick Chubb and Kareem Hunt, and the Browns are off to a 2-0 start.Pick: Browns 24, Jets 16Washington Commanders at Detroit Lions (-1.5)The Commanders are underdogs on the road despite a promising debut from Carson Wentz, who threw four TDs against the Jaguars. The Lions showed fight after digging a huge hole against the Eagles, and this is a must-win game of sorts for Dan Campbell in the early season. A last-second field goal either way.Pick: Commanders 24, Lions 21 Getty Images Tampa Bay Buccaneers (-2.5) at New Orleans SaintsThe Saints are 4-0 against Brady in the regular season since he joined Tampa Bay, though the Buccaneers did win the playoff matchup. The Bucs (152 rushing yards) and Saints ( Hunter Kampmoyer Jersey 151 rushing yards) ran the ball effectively in the opener, and whoever supports Tom Brady or Jameis Winston better in that regard wins this game. Tampa Bay has to finish in the red zone. This will come down to the last po se sion, and Brady delivers the win.Pick: Buccaneers 26, Saints 23Carolina Panthers at New York Giants (-2.5)The Giants have the opportunity to be the surprise 2-0 team of the early season under Brian Daboll. This will be another chance to reheat that 2018 NFL Draft debate between Baker Mayfield and Saquon Barkley, who had 194 total yards against the Titans in Week 1. Mayfield leads another comeback, but this one falls short.Pick: Giants 24, Panthers 22New England Patriots (-1.5) at Pittsburgh SteelersThere are some key injuries to sort out here, including Mac Jones (back) and Najee Harris (foot). The Steelers will be without T.J. Watt (pectoral muscle), so it's about generating a consistent pa s rush without their star player Keenan Allen T Shirts . The Patriots are the road favorite, but Pittsburgh pulls off another upset at the newly-minted Acrisure Stadium.Pick: Steelers 21, Patriots 20 (Getty Images) Indianapolis Colts (-4.5) at Jacksonville JaguarsThe Colts were a Week 1 dud in a tie against Tenne see given the talent Matt Ryan has to work with. They cannot afford a road slip-up against an improved Jacksonville team that will get better with each week. Doug Pederson and Frank Reich know each other well from the Super Bowl run in Philadelphia.Pick: Colts 28, Jaguars 21Miami Dolphins at Baltimore Ravens (-3.5)This could turn out to be the best game of the day. Lamar Jackson and Tua Tagovailoa were efficient in the opener, and they did that without the support of a trusty running game. The Mike McDaniel hype will be off the charts with a victory here, and there is enough support on the Dolphins roster to do it.Pick: Dolphins 26, Ravens 24Atlanta Falcons at Los Angeles Rams (-10.5)The Rams had a long layoff after the TNF lo s to Buffalo, and that should help sort out the options around Matthew Zander Horvath Jersey Stafford. It can't just be Cooper Kupp, even against the Falcons, who showed improvement with Marcus Mariota and a young roster.Pick: Rams 29, Falcons 21 Seattle Seahawks at San Francisco 49ers (-8.5)The 49ers were a dud in Trey Lance's opener, and Eli Mitchell's knee injury hurts the running game. Does that mean more Deebo Samuel in the backfield? The Seahawks have won the last four in this NFC West series, including the last three at San Francisco. This isn't a layup for San Francisco by any means.Pick: 49ers 27, Seahawks 24Cincinnati Bengals (-7) at Dallas CowboysThis was a virtual pick em before Dak Prescott's injury, and Cooper Rush is back in the fold as Dallas' answer at quarterback. The Bengals should bounce back after a disaster Week 1 in which Joe Burrow threw four interceptions. The matchup between Ja'Marr Chase and Trevon Diggs is an interesting subplot, JK Scott Jersey but Cincinnati rolls here.Pick: Bengals 31, Cowboys 20Houston Texans at Denver Broncos (-10)The new-look Broncos will make their home debut with Ru sell Wilson against Houston, which played Indianapolis to a tie. Davis Mills impre sed for the Texans, but he will be pre sed on the road. Houston averaged just 2.7 yards per rushing attempt in Week 1. That won't cut it against Denver.Pick: Broncos 28, Texans 19 Arizona Cardinals at Las Vegas Raiders (-3.5)The Cardinals and Raiders are among those playoff teams from last year hoping to avoid the 0-2 start. Both pa s defenses were shredded last week, albeit by elite quarterback play. Derek Carr and Kyler Murray should put on a high-scoring show in the afternoon window, but we'll stick with the home team. Josh McDaniels gets his first victory as Las Vegas coach.Pick: Raiders 31, Cardinals 24Chicago Bears at Green Bay Packers (-9.5)The Packers' Week 1 lo s to the Vikings was reminiscent of last year's lo s to the Saints. There is no reason for panic unle s Justin F