Tadalafil works by inhibiting the enzyme PDE5, which regulates blood flow in the penis. By blocking PDE5, it allows the blood vessels in the penis to relax and expand, facilitating increased blood flow and resulting in an erection when the man is sexually stimulated.Clinical studies have demonstrated that Tadalafil, including in the form of Megalis 10 mg, is effective in treating ED in a significant percentage of men. Its longer duration of action compared to some other ED medications allows for greater spontaneity in sexual activity.
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